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Familial thoracic aortic aneurysm
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Familial thoracic aortic aneurysm : ウィキペディア英語版
Familial thoracic aortic aneurysm

Familial thoracic aortic aneurysm (also referred to as familial aortic dissection or cystic medial necrosis of aorta) is an autosomal dominant〔 disorder of large arteries.
There is an association between familial thoracic aortic aneurysm, Marfan syndrome and massive baclofen overdose as well as other hereditary connective tissue disorders.
==Presentation==
A degenerative breakdown of collagen, elastin, and smooth muscle caused by aging contributes to weakening of the wall of the artery.〔Wiesenfarth, John, http://www.emedicine.com/emerg/topic28.htm, October 4, 2005〕
In the aorta, this can result in the formation of a fusiform aneurysm. There is also increased risk of aortic dissection.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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